Development, anti-proliferative activity, multi-target kinase inhibition against CHK1, PIM1, and CDK-2, and computational insights of new thiazole-based hybrids
Abstract
In the current medical landscape, multi-targeting by a single small molecule is recognized as an effective strategy in the fight against cancer.
Fields of Study & Subjects
Cancer Mechanisms and Therapy
Protein Degradation and Inhibitors
Synthesis and biological activity
Publication details
- Journal / source
- RSC Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 16
- Issue
- 16
- Pages
- 14010–14026
- Publication date
- 1 January 2026
- Language
- EN