Silica-incorporated cisplatin-MIP: synthesis, characterization, and evaluation via liquid chromatography

RSC Advances 2026 Open access

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Authors: Faiz Ali, Ilyas Ahmad, Musa Khan, Muhammad Rasul Jan, Zeid A. ALOthman, Munazzah, Won Jo Cheong
DOI: 10.1039/d6ra00977h
Cited by: 1
References: 69

Abstract

= 0.9923). Cisplatin adsorption is physisorption with heterogeneous multilayer formation in the cavities of the silica-based MIP, and this process is endothermic and spontaneous in nature. The imprinting factor of the silica-based MIP was found to be 2.11 with a particle size of the MIP in the sub-2 µm range. A liquid chromatographic system coupled with UV detection was used for investigating the selective nature of silica-based MIP towards cisplatin. Cisplatin was retained to a greater extent in contrast to other templates having structural similarities with cisplatin. The resultant MIP was applied for the removal of cisplatin from spiked real water samples, resulting in adsorption above 90%.

Fields of Study & Subjects

Analytical chemistry methods development Analytical Chemistry and Chromatography Mesoporous Materials and Catalysis

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
35
Pages
37003–37022
Publication date
1 January 2026
Language
EN