Antibacterial electrospun nanofibrous mats fabricated from polycaprolactone, gelatin and Synedrella nodiflora extract for biomedical applications
Abstract
, an initial moderate release was followed by sustained release, indicating controlled delivery without a significant burst effect. The Kirby-Bauer disk diffusion antibacterial test revealed that the control sample had no inhibitory effect, while the extract-impregnated mats exhibited a substantial antibacterial role against Gram-positive and Gram-negative bacteria, with an inhibitory zone diameter of 25.7 ± 0.6 and 30.3 ± 0.6 mm, respectively. Cytotoxicity analyses further verified an excellent biocompatibility and cell viability of >95%. Collectively, the developed PCL/GEL/SN electrospun nanofibrous mats could be used as antibacterial and biocompatible wound dressing materials.
Fields of Study & Subjects
Electrospun Nanofibers in Biomedical Applications
Advanced Cellulose Research Studies
Nanocomposite Films for Food Packaging
Publication details
- Journal / source
- RSC Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 16
- Issue
- 29
- Pages
- 26320–26333
- Publication date
- 1 January 2026
- Language
- EN