Nanotechnology in reproductive medicine: from gamete engineering to precision therapeutics

RSC Advances 2026 Open access

Read full text
Authors: Wenying Xu, Zhiyan Wang, Jiahui Lin, Longjie Li, H Wang, Pei Liu, Hao Hu, Chao He, Zijia Zheng, R M Liu, Kejun Dong, Donghui Huang
+1 more Xianjin Xiao
DOI: 10.1039/d6ra01614f
Cited by: 1
References: 157

Abstract

antioxidant nanoparticles, microfluidic sperm selection and improved cryopreservation-to targeted therapies for complex disorders including premature ovarian insufficiency, polycystic ovary syndrome, and endometriosis. Despite promising preclinical outcomes, clinical translation is impeded by challenges regarding biocompatibility, large-scale manufacturing, and ethical regulation. Future perspectives emphasize the integration of multi-omics, artificial intelligence, and biocompatible material innovation to elucidate molecular mechanisms and accelerate the transition from bench to bedside, ultimately advancing precision reproductive medicine.

Fields of Study & Subjects

Polymer Surface Interaction Studies Reproductive Biology and Fertility Nanoparticle-Based Drug Delivery

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
35
Pages
34319–34338
Publication date
1 January 2026
Language
EN