Ag–Sn@MOFs heterostructure enables ultrasensitive voltammetric determination of vismodegib in serum and urine

RSC Advances 2026 Open access

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Authors: Glowi Alasiri, Ali M. Alaseem, Razan Orfali, Ramadan Ali, Al‐Montaser Bellah H. Ali, Mohamed M. El-Wekil
DOI: 10.1039/d6ra01976e
Cited by: 1
References: 46

Abstract

= 0.9974). Importantly, the sensor maintained excellent accuracy in complex matrices, providing recoveries of 95.6-107.6% with precision ≤3.29% RSD in spiked human urine and serum, demonstrating strong matrix tolerance. The combination of scalable, low-toxicity fabrication with robust selectivity and stability highlights the platform's potential for VIS therapeutic monitoring, pharmacokinetic studies, and translation toward point-of-care diagnostics.

Fields of Study & Subjects

Metal-Organic Frameworks: Synthesis and Applications Molecular Sensors and Ion Detection Gold and Silver Nanoparticles Synthesis and Applications

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
26
Pages
23625–23636
Publication date
1 January 2026
Language
EN