Enzymatic electrochemiluminescence sensor based on a ternary luminol–H 2 O 2 -confined nanocatalyst system for sensitive determination of uric acid

RSC Advances 2026 Open access

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Authors: Chunchun Wei, Mixia Chen, W W Hu, Fei Yan, Yu Cui
DOI: 10.1039/d6ra02118b
Cited by: 4
References: 57

Abstract

, which is subsequently decomposed by the PtNPs-NGQDs nanocomposite, leading to enhanced ECL emission. Under optimized conditions, the sensor exhibits two linear response ranges for UA (0.01-1 µM and 1-50 µM) and a low detection limit of 8.1 nM (S/N = 3). The sensor also demonstrates good selectivity and stability, enabling reliable UA quantification in complex urine samples. This work provides a simple and versatile strategy for constructing sensitive ECL enzymatic platforms suitable for the detection of metabolites.

Fields of Study & Subjects

Advanced biosensing and bioanalysis techniques Electrochemical sensors and biosensors Advanced Nanomaterials in Catalysis

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
30
Pages
27756–27764
Publication date
1 January 2026
Language
EN