Tuning the hydrophobicity of glycine ester through N -acylation and introducing quaternary pyridinium groups enable the selectivity against Gram-positive bacteria

RSC Advances 2026 Open access

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Authors: Aleena Pious, Dharshini Karnan Singaravelu, Srimari Srikanth, Venkatasubramaian Ulaganathan, Chithra Sivanandan, Fadaa Alown, Fuád Ameén, Anbazhagan Veerappan
DOI: 10.1039/d6ra02317g
Cited by: 1
References: 31

Abstract

. The therapeutic potential was demonstrated by rescuing MRSA-infected zebrafish with QPyN16Ge, reducing the bacterial burden in the animals.

Fields of Study & Subjects

Peptidase Inhibition and Analysis Carbohydrate Chemistry and Synthesis Antimicrobial agents and applications

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
22
Pages
20216–20223
Publication date
1 January 2026
Language
EN