New fused tetracyclic ring systems: synthesis of 1-thia-4 a ,11,12-triazatetracenes via a multicomponent strategy, 2D-HMBC structural confirmation, and antimicrobial activity

RSC Advances 2026 Open access

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Authors: Reham E. Abdelwahab, Mostafa E. Salem, Mohammed Rashed Alsulami, Mona M. Soliman, Ismail A. Abdelhamid, Amr M. Abdelmoniem, Faisal K. Algethami, Ahmed H. M. Elwahy
DOI: 10.1039/d6ra03008d
Cited by: 1
References: 84

Abstract

A novel multicomponent synthesis of tetracyclic 1-thia-4 a ,11,12-triazatetracenes exhibit promising antimicrobial activity, with compound 9a emerging as a potent broad-spectrum lead supported by molecular docking studies.

Fields of Study & Subjects

Multicomponent Synthesis of Heterocycles Synthesis and Characterization of Heterocyclic Compounds Click Chemistry and Applications

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
28
Pages
25999–26011
Publication date
1 January 2026
Language
EN