Triple-amplified sequential activation allosteric DNA biosensor for in vivo quantitative detection of MYCN copy number in neuroblastoma

RSC Advances 2026 Open access

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Authors: Liang Zhao, Yingyu Zhang, Hengyun Tian, Mengxin Zhang, Kangbo Liu, Meng Sun, Zirong Li, Ligong Hou, Xianwei Zhang, Wancun Zhang
DOI: 10.1039/d6ra04840d
Cited by: 1
References: 31

Abstract

quantification of the M/N ratio in clinical NB tissues. In summary, this study presents a novel strategy for quantifying the NB M/N ratio, demonstrating significant potential for future applications in biomedical research and clinical diagnosis.

Fields of Study & Subjects

Neuroblastoma Research and Treatments Advanced biosensing and bioanalysis techniques Genomic variations and chromosomal abnormalities

Publication details

Journal / source
RSC Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
16
Issue
37
Pages
40708–40720
Publication date
1 January 2026
Language
EN