Photocatalytic multicomponent alkene dicarbofunctionalization via PCET/nickel dual catalysis

Chemical Science 2026 Open access

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Authors: Yeersen Patehebieke, Victoria Jansson, Jakob Öberg, Carl‐Johan Wallentin
DOI: 10.1039/d6sc00382f
Cited by: 1
References: 101

Abstract

) bond formation under visible light and redox-neutral conditions. The method proceeds directly from secondary and tertiary alcohols, exhibits broad functional-group tolerance. Notably, employing a chiral Ni catalyst enables the first enantioselective variant of this type of PCET mediated transformation. This work establishes a general platform for deconstructive alkene difunctionalization from simple alcohol feedstocks, expanding the synthetic reach of PCET in dual catalytic radical chemistry.

Fields of Study & Subjects

Radical Photochemical Reactions Catalytic C–H Functionalization Methods Catalytic Cross-Coupling Reactions

Publication details

Journal / source
Chemical Science
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
15
Pages
7690–7698
Publication date
1 January 2026
Language
EN