Photoinduced intramolecular S-α-C(sp 3 )–H functionalization enabled by an electron donor–acceptor complex-Mediated radical relay

Chemical Science 2026 Open access

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Authors: Tiantian Xu, Ran Hong, Tong Lü, Denghua Zhu, Jiong Yu, Min Wang, Pinhua Li
DOI: 10.1039/d6sc01281g
Cited by: 3
References: 56

Abstract

We describe a consecutive reaction of 2-alkynylthioanisoles and 4-cyanopyridine enabled by EDA complex photoactivation, which facilitates the sequential S-α-C(sp 3 )–H bond activation, cyclization and radical coupling under mild conditions.

Fields of Study & Subjects

Radical Photochemical Reactions Catalytic C–H Functionalization Methods Sulfur-Based Synthesis Techniques

Publication details

Journal / source
Chemical Science
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
17
Pages
8683–8691
Publication date
1 January 2026
Language
EN