Achiral benzoic acid appended helical polymers for the copper-catalyzed asymmetric Diels–Alder reaction and Michael addition with excellent enantioselectivity and recyclability
Abstract
-configured product. Regulating the backbone helicity could control the direction of enantioselectivity and enantiomeric products could be facilely obtained using helical polyisocyanide with opposite handedness. Importantly, catalysts can be readily precipitated from the reaction mixture by addition of a poor solvent and reused for five consecutive cycles without significant loss of yield and enantioselectivity. After copper leaching and re-coordination, they can be cyclically applied to distinct asymmetric reactions.
Fields of Study & Subjects
Synthesis and Properties of Aromatic Compounds
Axial and Atropisomeric Chirality Synthesis
Covalent Organic Framework Applications
Publication details
- Journal / source
- Chemical Science
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 17
- Issue
- 17
- Pages
- 8733–8743
- Publication date
- 1 January 2026
- Language
- EN