AgBF 4 -catalyzed insertion of unactivated alkynes into C–F bonds of acyl fluorides
Abstract
-selectivity. Given that monofluoroalkenes are valuable amide bioisosteres, this method enables direct access to bio-relevant motifs from carboxylic acid derivatives and supports late-stage monofluoroalkene installation in complex molecules.
Fields of Study & Subjects
Fluorine in Organic Chemistry
Inorganic Fluorides and Related Compounds
Synthesis and Characterization of Pyrroles
Publication details
- Journal / source
- Chemical Science
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 17
- Issue
- 25
- Pages
- 12604–12608
- Publication date
- 1 January 2026
- Language
- EN