Aerobic C–H bond activation at a Pd center under aqueous conditions

Chemical Science 2026 Open access

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Authors: Dae Young Bae, Nicholas P. Ruhs, Liviu M. Mirica
DOI: 10.1039/d6sc03081e
Cited by: 0

Abstract

Facile aerobic C–H activation proceeds at a Pd center under aqueous conditions. Water-assisted hydrogen bonding lowers the activation barrier, and combined experimental and DFT studies identify the C–H bond activation as the rate-determining step.

Fields of Study & Subjects

Asymmetric Hydrogenation and Catalysis Chemical Reactions and Isotopes Catalytic C–H Functionalization Methods

Publication details

Journal / source
Chemical Science
Volume
17
Issue
27
Pages
13539–13549
Publication date
1 January 2026
Language
EN