Nanopore sequencing with proteins: synchronization and dischronization of molecular dynamics simulations with laboratory and industrial developments

Soft Matter 2026

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Authors: Zongan Wang, Yuqian Liu, Tao Zeng, Denghui Li, Xiao Shi, Jiawen Zhang, Hao Wang, Liuxin Shi, Jiayuan Zhang, Yinqi Bai, Yuning Zhang, Yuliang Dong
DOI: 10.1039/d6sm00125d
Cited by: 1
References: 184

Abstract

This review traces the experimental evolution of three protein nanopores for sequencing, revealing that molecular dynamics simulations consistently lag behind industrial developments and proposing research directions to close the gap.

Fields of Study & Subjects

Nanopore and Nanochannel Transport Studies Ion-surface interactions and analysis RNA and protein synthesis mechanisms

Publication details

Journal / source
Soft Matter
Publisher
Royal Society of Chemistry (RSC)
Volume
22
Issue
31
Pages
5135–5161
Publication date
1 January 2026
Language
EN