Tyrosine-capped gold nanoparticles enable cysteine-free peptide loading, enhancing the antipseudomonal efficacy of scorpion-derived AamAP1-Lys-NH 2 in a burn wound infection model

Journal of Materials Chemistry B 2026 Open access

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Authors: Rosalind J. van Wyk, Mandelie van der Walt, June Cheptoo Serem, A. James Mason, M E Bester, Anabella R. M. Gaspar
DOI: 10.1039/d6tb00168h
Cited by: 1
References: 56

Abstract

-AuNPs as a promising therapeutic candidate for the topical treatment of infected wounds, with the Tyr-AuNP platform enabling efficient peptide loading while preserving antimicrobial activity, enhancing stability and minimising cytotoxicity.

Fields of Study & Subjects

Antimicrobial Peptides and Activities Wound Healing and Treatments Graphene and Nanomaterials Applications

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
27
Pages
8427–8443
Publication date
1 January 2026
Language
EN