Melanocortin 1 receptor-targeted peptide-functionalized liposomes for enhanced melanocyte-preferential drug delivery and anti-melanogenic efficacy

Journal of Materials Chemistry B 2026

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Authors: Donghan Kim, Hwira Baek, Marta Gonçalves, Seyoung Yang, Seungjae Lee, Kyeongdeok Jang, Yun H Hwang, Jae Sung Hwang, Youngbok Lee, Jin Woong Kim
DOI: 10.1039/d6tb00172f
Cited by: 1
References: 35

Abstract

results in melanin reduction and decreased tyrosinase expression. These findings indicate that MC1R-targeted liposomal delivery achieves melanocyte-preferential internalization and anti-melanogenic efficacy, suggesting translational potential in the topical management of pigmentary disorders and cosmetic depigmentation applications.

Fields of Study & Subjects

melanin and skin pigmentation Regulation of Appetite and Obesity RNA Interference and Gene Delivery

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
28
Pages
8818–8828
Publication date
1 January 2026
Language
EN