A suturable multilayered fibrous scaffold loaded with α-ketoglutarate for enhanced bone regeneration
Abstract
. In a rat calvarial defect model, the membrane significantly accelerated bone regeneration through the synergistic effects of osteogenesis, immunomodulation, and angiogenesis. This work provides a novel structure-function cooperative design strategy and offers a guiding framework for future development of personalized, temporally controlled smart bone regeneration materials.
Fields of Study & Subjects
Bone Tissue Engineering Materials
Periodontal Regeneration and Treatments
Graphene and Nanomaterials Applications
Publication details
- Journal / source
- Journal of Materials Chemistry B
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 14
- Issue
- 18
- Pages
- 5680–5695
- Publication date
- 1 January 2026
- Language
- EN