Wearable near-infrared LED photothermal microneedle patch reduces periorbital wrinkles in a randomized pilot clinical trial

Journal of Materials Chemistry B 2026 Open access

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Authors: Hyo-Won Han, 이동환, Ara Joe, Yeong Jun Jeon, Yu-Ra Lim, Sang Bong Lee, Bumho Bin, JuKyung Lee, Thavasyappan Thambi, João Conde, Manivasagan Panchanathan, Eue‐Soon Jang
DOI: 10.1039/d6tb00534a
Cited by: 1
References: 49

Abstract

∼1.9% improvement at week 4). No device-related adverse events were observed. By decoupling penetration from actuation through a plasmonic nanocomposite backing, this platform transforms dissolving microneedles into programmable, eyelid-compatible transdermal devices with human evidence, suggesting broad utility for gentle, controllable delivery at sensitive sites.

Fields of Study & Subjects

Advancements in Transdermal Drug Delivery Dermatologic Treatments and Research Ocular Surface and Contact Lens

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
25
Pages
7985–7999
Publication date
1 January 2026
Language
EN