Vortex-enhanced bone regeneration: gyroid gradient scaffolds tune permeability for hemodynamic-accelerated osseointegration

Journal of Materials Chemistry B 2026

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Authors: Yun Zhao, Zuohua Ren, Lichi Guo, Ruochen Duan, Mingyi Li, Dongni Liu, Shengwei Zhang
DOI: 10.1039/d6tb00772d
Cited by: 1
References: 30

Abstract

SLM were implanted into rat tibial defects. Radiographic and histological analyses demonstrated 35% greater new bone area in the gradient group, with histological sections revealing uniform osteoblast distribution and mature bone matrix deposition, confirming hemodynamic-accelerated osseointegration. This work establishes a "simulation-design-fabrication-validation" pipeline, providing a paradigm for personalized bone scaffolds with tunable permeability to optimize clinical outcomes.

Fields of Study & Subjects

Periodontal Regeneration and Treatments Heterotopic Ossification and Related Conditions Bone Tissue Engineering Materials

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
26
Pages
8302–8316
Publication date
1 January 2026
Language
EN