A multi-target nano-therapy against cerebral ischemia/reperfusion injury via combinatorial inhibition of neuroinflammation and pyroptosis

Journal of Materials Chemistry B 2026

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Authors: Wenchao Fu, Ayang Zhao, Bo Chen, Yu Feng, Hongliang Shen, Jietao Li, Xianzhang Zeng
DOI: 10.1039/d6tb00794e
Cited by: 1
References: 34

Abstract

: we successfully developed an "active targeting-multi-drug synergy-cascade intervention" nano-therapeutic platform that effectively mitigates cerebral I/R injury through multi-pathway coordination, offering a novel combinatory strategy for ischemic stroke treatment.

Fields of Study & Subjects

Inflammasome and immune disorders Neuroinflammation and Neurodegeneration Mechanisms Inflammation biomarkers and pathways

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
29
Pages
9144–9158
Publication date
1 January 2026
Language
EN