Fabrication of bilayer nerve conduits with sustained drug release using a multi-material, embedded 3D printing strategy

Journal of Materials Chemistry B 2026 Open access

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Authors: Betty Cai, Sadegh Ghorbani, Lili He, David Kilian, Wen-Chieh Chao, Jon‐Paul Pepper, Sarah C. Heilshorn
DOI: 10.1039/d6tb01916a
Cited by: 1
References: 67

Abstract

NGF release and bioactivity assays. Finally, we demonstrated the fabrication of bilayer conduits with branched and multi-lumen geometries, which are challenging to fabricate with existing strategies. Altogether, these results highlight the promise of 3D printed nerve conduits leveraging tunable biomaterials to both physically guide and biochemically promote nerve regeneration.

Fields of Study & Subjects

Nerve injury and regeneration Neuroscience and Neural Engineering 3D Printing in Biomedical Research

Publication details

Journal / source
Journal of Materials Chemistry B
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
35
Pages
10938–10950
Publication date
1 January 2026
Language
EN