Potential of Nanoparticels Dayak Onion (Eleutherine palmifola) as an Immunomodulator for Supporting Spleen Tissue Growth and Broiler Performance

The aim is to analyse the potential of nanoparticles in Dayak Onion as an immunomodulator in supporting spleen tissue growth and improving broiler production performance. The research material is nanoparticles Dayak Onion (NPDO) and broiler. The treatment was administered of NPDO 1%, 2%, 3%, positive and negative (control). The research method is experimental. The variable are immune response, spleen tissue and broiler production performance. The Research design is completely randomized. Data were analysed using Analysis of Variance and followed by the Duncan Test (5%). The treatment had a significant effect (P < 0.05) on the immune response (Ig G and Ig Y). The highest concentration of Ig G was in the Negative Control (36.64 g/L), while the highest concentration of Ig Y was in NPDO 3% (22 g/L). The best increase in spleen weight was observed at NPDO 3% (2.81g), and the lowest tissue damage score was recorded at NPDO 3% (1.7%). NPDO does not affect broiler performance, as measured by average weight gain (AWG) and index performance (IP). The conclusion is that NPDO provide a good response to immunity and supporting spleen tissue, but not to broiler performance production. NPDO as a feed additive for immunomodulators' broilers is recommended to be given at 3% of the basal feed.