Indirect spectrophotometric estimation of lidocaine using crystal violet

A simple, quick and perceptive method was developed to estimate Lidocaine in its pure and pharmaceutical forms spectrally using a spectrometer for ultraviolet visible rays, and the method was summarized: by oxidation of the drug using a mixture of bromate and potassium bromide KBr-KBrO3 with an acidic medium, where the remaining oxidizing agent reacts with the dye Crystal violet (CV) to be a dark blue product It gave peak absorption value at 612 nm, with Beer-lambert law (linear concentration) was between (15) and (100) μg/ml while the molar absorption coefficient was equal to (1945.022) L/mol/cm , limit of detection (0.36) μg/ml, while the quantity limit was (1.08) μg/ml. The method has been effictively applied to the measurement of Lidocaine in both its pure form and its pharmaceutical preparations.