Allocation of Kidney Allografts From Donors With Kidney Donor Profile Index <35% and the Impact of Kidney Donor Profile Index Revisions on Access to Transplantation for Children

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Authors: Elizabeth M. Sonnenberg, Sandra Amaral, Siqi Zhang, Jeremy Rubin, Matthew H. Levine, Vishnu S. Potluri
Cited by: 1
References: 35

Abstract

RATIONALE & OBJECTIVE: Children in the United States receive priority for kidneys with a kidney donor profile index (KDPI) < 35%, although their priority falls below that of certain adult recipients. Recently, the KDPI was revised to include 8 donor characteristics instead of 10. We sought to (1) describe the allocation of these high-quality kidneys and (2) compare the characteristics of donors with a KDPI < 35% using the original KDPI (KDPI-10) versus the revised KDPI (KDPI-8) calculation. STUDY DESIGN: Retrospective cohort study. SETTING & PARTICIPANTS: 60,587 deceased donors and their kidney recipients in the Organ Procurement and Transplantation Network registry between January 1, 2018, and December 31, 2023. EXPOSURE: KDPI calculated using KDPI-10 and KDPI-8 (without race and hepatitis C virus [HCV]). OUTCOME: The primary outcome was the use of kidneys with a KDPI < 35% overall. Secondary outcome was the utilization of kidneys from "ideal pediatric-quality donors" who were defined as having a KDPI < 35%, diagnosed with brain death, were aged

Fields of Study & Subjects

Organ Donation and Transplantation Renal Transplantation Outcomes and Treatments Organ Transplantation Techniques and Outcomes

Publication details

Journal / source
American Journal of Kidney Diseases
Publisher
Elsevier BV
Volume
88
Issue
2
Pages
206–216.e1
Publication date
21 April 2026
Language
EN