Progression of Pancreatic Morphologic Changes and Endocrine Dysfunction After Acute Pancreatitis: Preliminary Results of the Longitudinal Goulash-Plus Cohort Study

Gastroenterology 2026 Open access

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Authors: Alexandra Mikó, Nelli Farkas, Áron Vincze, Ferenc Izbéki, Andrea Szentesi, Péter Jenő Hegyi, Péter Jenő Hegyi, Noémi Gede, Vivien Vass, Dalma Dobszai, László Gajdán, Veronika Lillik
+75 more Patrícia Sarlós, Beáta Bódis, Emese Sipter, Dániel Pécsi, Katalin Márta, Dorottya Tarján, Bálint Erőss, Nándor Faluhelyi, Péter Jenő Hegyi, Péter Jenő Hegyi, Marie Engh, Mária Papp, Péter Mátrai, Zsolt Abonyi-Tóth, Miklós Sahin-Tóth, Ole H. Petersen, Markus M. Lerch, John P. Neoptolemos, Kálmán Tóth, Erzsébet Lankó, Péter Kanizsai, Szilárd Váncsa, Rita Nagy, Benedek Tinusz, Erős Adrienn, Zsolt Szakács, Péter Varjú, Lajos Szakó, Noémi Zádori, Lajos Szakó, Alexandra Bálint, Brigitta Teutsch, Andrea Párniczky, Dóra Mosztbacher, Szilárd Gódi, Judit Bajor, József Czimmer, Imre Szabó, Anita Illés, Gabriella Pár, Roland Hágendorn, Zsolt Márton, Tamás Nagy, Attila Miseta, András Vereczkei, Dezső Kelemen, Veronika Dunás-Varga, Adrienn Halász, Roland Fejes, Pál Maurovics-Horvát, Pál Ákos Deák, Ibolya Kocsis, Barna Vásárhelyi, László Zubek, Z. Molnar, Fruzsina Petlickij, Klaudia Káplár, Zoltán Hajnády, Olga Júlia Zahariev, Bettina Csilla Budai, Luca Havelda, Tamás Hussein, Balázs Lázár, Péter Sahin, Tamás Tornai, Mónika Lipp, Emese Fürst, Edina Tari, Orsolya Eperjesi, Zoltán Bánfalvi, Boglárka Barna, Orsolya Urbán, Zita Kormos, Laura Toth, Andrea Harnos
DOI: 10.1053/j.gastro.2025.09.034
Cited by: 4
References: 10

Abstract

Approximately 96% to 98% of patients survive acute pancreatitis (AP),1 yet many are exposed to significant long-term risks that are often overlooked. AP may be followed by recurrent acute pancreatitis (RAP) episodes and early chronic pancreatitis (ECP), which can eventually progress to chronic pancreatitis (CP).2,3 Progression of endocrine dysfunction, defined as the combined proportion of newly diagnosed prediabetes and diabetes mellitus (DM), may also reach 35% in the first year after the first AP episode and 59% in the fifth year.

Fields of Study & Subjects

Pancreatitis Pathology and Treatment Pancreatic and Hepatic Oncology Research Dermatological and COVID-19 studies

Publication details

Journal / source
Gastroenterology
Publisher
Elsevier BV
Volume
170
Issue
3
Pages
631–634
Publication date
20 January 2026
Language
EN