Indexed Delivery of Oxygen Predicts In-hospital Mortality and Morbidity in Reoperative Adult Cardiac Surgery Patients: A Retrospective Cohort Study

Journal of Cardiothoracic and Vascular Anesthesia 2026 Open access

Read full text
Authors: Antonino Salvatore Rubino, Luca Salvatore De Santo, Michele Torella, Antonio Pio Montella, Caterina Golini Petrarcone, Lucrezia Palmieri, Denise Galbiati, Antonio Pisano, Federico Pappalardo, Marisa De Feo
DOI: 10.1053/j.jvca.2026.01.002
Cited by: 0
References: 21

Abstract

OBJECTIVES: To evaluate the association between intraoperative indexed oxygen delivery (DO₂i) during cardiopulmonary bypass (CPB) and postoperative outcomes in patients undergoing reoperative cardiac surgery. DESIGN: Retrospective cohort study. SETTING: A tertiary academic cardiac surgery center. PARTICIPANTS: A total of 343 patients who underwent reoperative cardiac procedures between January 2011 and January 2021. INTERVENTIONS: Patients were stratified by the median DO₂i threshold predictive of in-hospital mortality, identified using Youden's Index. MEASUREMENTS AND MAIN RESULTS: Median DO₂i was 300.8 ± 52.3 mL/min/m². In-hospital mortality was 14.6%. A median DO₂i

Fields of Study & Subjects

Cardiac and Coronary Surgery Techniques Sepsis Diagnosis and Treatment Respiratory Support and Mechanisms

Publication details

Journal / source
Journal of Cardiothoracic and Vascular Anesthesia
Volume
40
Issue
5
Pages
1373–1380
Publication date
3 January 2026
Language
EN