Transcolonic endoscopic appendectomy using a novel integrated snare-knife device: a case report

A 57-year-old woman presented with an incidental 5 mm protrusion at the appendiceal orifice, identified during a routine examination. The asymptomatic patient had no notable medical history. Under non-intubated anesthesia with the patient positioned in the left lateral decubitus position, the procedure was initiated with a submucosal injection utilizing the integrated needle mode. Furthermore, a circumferential incision was created followed by full-thickness dissection with intermittent electrocoagulation. Meanwhile, the minimal purulent material was encountered during peritoneal entry. The appendiceal mesentery was systematically divided utilizing the knife function, followed by complete resection of the appendix and specimen retrieval with the integrated snare. Post-resection, the enterotomy was closed utilizing a glove-derived rubber band traction system combined with endoscopic suturing. Additionally, a drainage catheter was deployed under direct visualization ([ Fig. 1 ]). Within 30 minutes, appendiceal resection was completed and the total procedural duration was only 60 minutes ([ Video 1 ]). Fig. 1 Transcolonic endoscopic appendectomy using the snare probe throughout the procedure. a Protruding lesions adjacent to the appendix. b Mucosal incision. c Submucosal injection. d Coagulation for hemostasis. e Conversion to the snare for appendiceal resection. f Application of the traction clip for wound closure. g Appendix removed by snare mode. h The resected specimen. Download Video Transcolonic endoscopic appendectomy using a novel integrated snare-knife device.Video 1 Histopathological analysis confirmed chronic inflammation of the appendix with associated abscess formation. The patient experienced no postoperative discomfort. A follow-up colonoscopy performed 4 months later demonstrated good healing of the surgical incision ([ Fig. 2 ]). Fig. 2 Colonoscopy images at a 4-month postoperative follow-up. This represents the first documented utilization of a multifunctional snare probe combining the electrosurgical knife, snare, and injection needle capabilities in NOTES appendectomy [ 1 ] [ 2 ] [ 3 ]. Endoscopy_UCTN_Code_TTT_1AT_2AZ Publication History Article published online: 08 January 2026 © 2026. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/). Georg Thieme Verlag KG Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany