Neurodevelopmental Outcome after Late-Onset Bacterial Sepsis in Infants Born before 29 Weeks' Gestation

American Journal of Perinatology 2026

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Authors: Smita Roychoudhury, Abhay Kumar Lodha, Anne R. Synnes, Joseph Ting, Sajit Augustine, Jehier K. Afifi, Victoria Bizgu, Xiang Y. Ye, Prakesh S. Shah, Amuchou Singh Soraisham, Prakesh S. Shah, Marc Beltempo
+42 more Jaideep Kanungo, Jonathan Wong, Miroslav Stavel, Rebecca L. Sherlock, Ayman Abou Mehrem, Jennifer Toye, Joseph Ting, Carlos Fajardo, Jaya Bodani, Lannae Strueby, Mary K Seshia, Deepak Louis, Ruben E. Alvaro, Ann Yi, Amit Mukerji, Orlando Da Silva, Sajit Augustine, Kyong-Soon Lee, Eugene Ng, Brigitte Lemyre, Thierry Daboval, Faiza Khurshid, Victoria Bizgu, Keith James Barrington, Anie Lapointe, Guillaume Éthier, Christine Drolet, Martine Claveau, Marie St‐Hilaire, Valérie Bertelle, Édith Massé, Caio Barbosa de Oliveira, Hala Makary, Cecil Ojah, Alana Newman, Jo-Anna B. J. Hudson, Jehier K. Afifi, Andrzej Kajetanowicz, Bruno Piedbœuf, the Canadian Neonatal Network and Canadian Neonatal Follow-Up Network TM, Canadian Neonatal Network Investigators, Canadian Neonatal Network Investigators
DOI: 10.1055/a-2779-7133
Cited by: 0
References: 39

Abstract

Objective: Neonatal late-onset sepsis is associated with increased mortality and morbidity, adversely impacting long-term outcome. The objective of this study was to examine neurodevelopmental (ND) outcomes at 18 to 24 months' corrected age (CA) in infants with late-onset bacterial sepsis (LOS) and to categorize outcomes based on type of bacterial pathogen in a cohort of preterm infants born less than 29 weeks gestation in Canada. Study Design: We conducted a retrospective cohort study of all non-anomalous infants born at

Fields of Study & Subjects

Neonatal and Maternal Infections Infant Development and Preterm Care Neonatal and fetal brain pathology

Publication details

Journal / source
American Journal of Perinatology
Volume
43
Issue
11
Pages
1441–1449
Publication date
29 January 2026
Language
EN