A Practical Synthesis of 3-Ylidenephthalides by the Rh-Catalyzed Tandem Reactions of Benzoic acids and Alkynyl Chlorides

Synthesis 2026

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Authors: Huan Yu Jin, Tingyu Zhang, Yingjie Zuo, Xu Zhao, Fang Li, Yunfei Luo
DOI: 10.1055/a-2784-2363
Cited by: 0
References: 30

Abstract

Abstract A synthesis of 3-ylidenephthalides with high practicality and efficiency, using benzoic acids and alkynyl chlorides as substrate, was realized by the rhodium catalysis. The utilization of alkynyl chlorides enabled this reaction has advantages of broad substrates scope, mild reaction condition, high selectivity, and yields.

Fields of Study & Subjects

Catalytic Alkyne Reactions Catalytic C–H Functionalization Methods Catalytic Cross-Coupling Reactions

Publication details

Journal / source
Synthesis
Volume
58
Issue
08
Pages
939–944
Publication date
9 January 2026
Language
EN