Catalytic Asymmetric Construction of Medium-Sized Ring Systems with Single Axial or Inherent Chiral Element
Abstract
Abstract Inherently and axially chiral medium-sized cyclic compounds play an essential role across multiple domains—from medicinal chemistry and advanced materials to asymmetric catalysis—due to their unique structural and functional properties. With rapid innovation in synthetic methodologies over recent years, this review provides a systematic summary and discussion of representative advances in the synthesis of medium-sized ring systems featuring single axial or inherent chirality.
Fields of Study & Subjects
Axial and Atropisomeric Chirality Synthesis
Asymmetric Synthesis and Catalysis
Cyclopropane Reaction Mechanisms
Publication details
- Journal / source
- Synthesis
- Volume
- 58
- Issue
- 12
- Pages
- 1321–1342
- Publication date
- 4 February 2026
- Language
- EN