Ruthenium-catalyzed C–H Sulfonamidation of 4-Aryl-7H-pyrrolo[2,3-d] pyrimidine with Sulfonyl Azides Under Aerobic Atmosphere

Synlett 2026

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Authors: Chunfeng Li, Chenhong Pan, Bin Liu, Chunwei Shen, Xingxian Zhang
DOI: 10.1055/a-2797-9503
Cited by: 0
References: 45

Abstract

Abstract Ruthenium-catalyzed arene ortho C−H sulfonamidation of 4-aryl-7H-pyrrolo[2,3-d]pyrimidine derivatives with sulfonyl azides under aerobic conditions is described. This transformation has the advantages of operational simplicity, good functional group compatibility, broad substrate scope, and mild conditions, affording a variety of sulfonamidated pyrrolo[2,3-d]pyrimidine derivatives in good to excellent yields. Oxygen plays a vital role in this unique reactivity.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Sulfur-Based Synthesis Techniques Synthesis and Catalytic Reactions

Publication details

Journal / source
Synlett
Volume
37
Issue
06
Pages
739–745
Publication date
27 January 2026
Language
EN