AgNO3/K2S2O8-Promoted Decarboxylative Oxyphosphorylation of Cinnamic Acids: A Mild Synthesis of β-Ketophosphonates
Abstract
Abstract This works reports an efficient and general method for synthesizing β-ketophosphonate derivatives using AgNO3 as the catalyst and K2S2O8 as the oxidant under mild conditions (room temperature and open-air atmosphere). The procedure is effective under simple and very convenient conditions with easy isolation and purification of the product. Potassium persulfate (K2S2O8) has emerged as a cost-effective, easily accessible inorganic oxidant. K2S2O8 exhibited a unique utility as the most efficient oxidant due to its greater solubility in organic media. A broad substrate scope and suitable functional group compatibility were observed. Experimental studies show that the reaction undergoes a radical process.
Fields of Study & Subjects
Organophosphorus compounds synthesis
Oxidative Organic Chemistry Reactions
Phosphorus compounds and reactions
Publication details
- Journal / source
- Synthesis
- Volume
- 58
- Issue
- 11
- Pages
- 1251–1258
- Publication date
- 4 March 2026
- Language
- EN