Recent Advances in the Synthesis and Utility of 1,1-Dibromoolefins

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Authors: Arthur Flaget, Mark Lautens, Andrew Gregory Durant, Lukas J. Glofcheskie, Julian K Fernback
Cited by: 1
References: 231

Abstract

Abstract 1,1-Dibromoolefins represent an important motif for synthetic chemists. Each carbon–bromine bond represents a reactive handle that can be differentially functionalized to increase molecular complexity from simple starting materials. They can be used for the synthesis of a variety of heterocycles, densely functionalized olefins, and alkynes. Facile access to this functional group can be achieved from a corresponding carbonyl compound, an olefin, or an alkyne. This graphical review provides a broad overview of the synthesis and synthetic utility of this important functional group since 2011. It covers their reactivity with metal catalysts as well as in metal-free reactions.

Fields of Study & Subjects

Catalytic Cross-Coupling Reactions Catalytic Alkyne Reactions Catalytic C–H Functionalization Methods

Publication details

Journal / source
SynOpen
Publisher
Georg Thieme Verlag KG
Volume
10
Issue
01
Pages
92–136
Publication date
20 February 2026
Language
EN