Post-Epileptic Ischemic Stroke (PEIS): pathophysiological conditions of ischemic stroke events due to epileptic seizures

Fortschritte der Neurologie · Psychiatrie 2026

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Authors: Andreas Posa, Ole Hensel, Walter Alexander Wohlgemuth, Gumash Babayeva, Malte Erich Kornhuber
DOI: 10.1055/a-2816-4615
Cited by: 1
References: 35

Abstract

Abstract: The most common cause of epileptic seizures in adults over the age of 60 is cerebrovascular disease, such as stroke. Although there are many studies of epilepsy after stroke, there are few data on the reverse causality (Post-Epileptic Ischemic Stroke, PEIS). Interestingly, in this constellation, sometimes no correlating vascular abnormalities can be identified as the hemodynamic cause for the ischemic stroke. We review the pathophysiological mechanisms of PEIS and highlight the diagnostic and therapeutic relevance of PEIS for daily clinical practice to raise clinical awareness of such events.

Fields of Study & Subjects

Epilepsy research and treatment Pharmacological Effects and Toxicity Studies Neurological and metabolic disorders

Publication details

Journal / source
Fortschritte der Neurologie · Psychiatrie
Publisher
Georg Thieme Verlag KG
Volume
94
Issue
05
Pages
190–192
Publication date
3 March 2026
Language
DE