Multi(aryl)methyl-Substituted 1,10-Phenanthrolines: Synthesis and Application to Ir-Catalyzed Alkane C(sp3)–H Borylation with HBpin
Abstract
Abstract A series of 1,10-phenanthroline derivatives bearing multi(aryl)methyl substituents was synthesized and applied to the Ir-catalyzed C(sp3)–H borylation of alkanes using HBpin. Some Ir complexes bearing the developed 1,10-phenanthroline ligands exhibited superior catalytic activity compared with those containing conventional 1,10-phenanthroline ligands, such as 3,4,7,8-tetramethyl-1,10-phenanthroline and 2-methyl-1,10-phenanthroline. These studies revealed that 3,8-multi(aryl)methyl-substituted 1,10-phenanthrolines are crucial for catalytic activity, and that the steric bulk of the multi(aryl)methyl groups significantly influences the catalytic performance.
Fields of Study & Subjects
Catalytic C–H Functionalization Methods
Organoboron and organosilicon chemistry
Catalytic Cross-Coupling Reactions
Publication details
- Journal / source
- Synthesis
- Publisher
- Georg Thieme Verlag KG
- Volume
- 58
- Issue
- 18
- Pages
- 2117–2122
- Publication date
- 24 April 2026
- Language
- EN