Does preoperative vitamin D-status affect patient-reported outcome measures and clinical parameters in hip, knee, and shoulder arthroplasty?

Introduction: Vitamin D is essential for calcium homeostasis and healthy bone metabolism. The osseointegration of endoprosthetic implants largely depends on good bone quality. To date, it is unclear whether preoperative vitamin D deficiency is associated with poorer patient-reported outcome measures (PROMs) and unfavorable clinical parameters in patients scheduled for total joint arthroplasty. For this reason, the aim was to examine these associations in the context of prehabilitation (fast-track setting). Methods : We conducted a prospective single-center cohort study (April–December 2024) involving 912 consecutive patients who underwent total joint arthroplasty of either the hip, knee, or shoulder: (primary and revision surgery). Preoperative vitamin D- calcium and parathyroid hormone status were assessed. Various PROMs (WOMAC, EQ scales, OHS/OKS, and DASH) and data from the electronic health record, including ASA score, were collected. Moreover, vitamin D supplementation of patients was assessed. Data was correlated to clinical endpoints such as cementation type, length of stay (LOS) and 6-month readmissions. Results : Cohort: Men 43.6%, women 56.4%, average age 67.7 years. Vitamin D available in 832 (91.2%): 28.0± 13.7 ng/ml; deficient (