Single-Stage Expanded Endonasal Resection of Giant Craniopharyngioma
Abstract
A 52-year-old male presented with several months of altered mental status, confusion, and memory impairment. Imaging demonstrated a tuberoinfundibular craniopharyngioma with significant extension into the third and lateral ventricles, leading to pituitary dysfunction and cognitive decline. A staged approach was considered in the event of incomplete resection. The patient underwent expanded endoscopic endonasal resection with planned pituitary sacrifice. Two small residual foci of enhancement adherent to the bilateral hypothalami were planned for subsequent radiosurgery treatment. Publication History Article published online: 27 February 2026 © 2026. Thieme. All rights reserved. Georg Thieme Verlag KG Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
Fields of Study & Subjects
Pituitary Gland Disorders and Treatments
Head and Neck Surgical Oncology
Neuroendocrine Tumor Research Advances
Publication details
- Journal / source
- Journal of Neurological Surgery Part B Skull Base
- Volume
- 87
- Issue
- S 01
- Pages
- S1–S548
- Publication date
- 27 February 2026
- Language
- EN