Patient Frailty as A Predictor of Outcomes Following Preoperative Embolization for Skull Base Meningioma Resection

Background: Pre-operative embolization is frequently used for skull base meningiomas to decrease intraoperative bleeding, improve surgical visibility, and facilitate maximal safe resection. However, the impact of patient frailty on embolization efficacy, perioperative safety, and long-term outcomes has not been well defined. The modified Frailty Index (mFI-5) provides a standardized measure to stratify patients by physiologic reserve. Objective: To assess how frailty impacts embolization performance, perioperative safety, functional outcomes, and long-term symptom burden in skull base meningioma patients, and to evaluate its predictive value for complications and discharge disposition. Methods: We retrospectively reviewed 35 patients who underwent pre-operative embolization followed by surgical resection for skull base meningiomas. Patients were stratified into low frailty (mFI-5