Surgical Outcomes of Endoscopic Endonasal Surgery for Nonfunctioning Pituitary Neuroendocrine Tumors in Elderly Patients: A Comprehensive Analysis Beyond Age
Abstract
Objective: Due to the rapid aging of the global population, it is challenging to identify elderly individuals who are optimal candidates for the surgical treatment of pituitary neuroendocrine tumors. While chronological age has traditionally influenced surgical decision-making, the independent effect of age on outcomes requires a comprehensive evaluation that controls for comorbidities and tumor characteristics. Methods: This retrospective analysis included 305 patients (≥18 years) who underwent endoscopic endonasal surgery for clinically nonfunctioning pituitary neuroendocrine tumors between March 2020 and February 2024 at a single tertiary center. Patients were stratified by age (
Fields of Study & Subjects
Pituitary Gland Disorders and Treatments
Head and Neck Surgical Oncology
Neuroendocrine Tumor Research Advances
Publication details
- Journal / source
- Journal of Neurological Surgery Part B Skull Base
- Volume
- 87
- Issue
- S 01
- Pages
- S1–S548
- Publication date
- 27 February 2026
- Language
- EN