Cavernous Sinus Exenteration and Radical Neck Dissection for Dedifferentiated Adenoid Cystic Carcinoma with Neuroendocrine Features: A Multidisciplinary Approach
Abstract
We present a multidisciplinary case of a 35-year-old female who had a parapharyngeal mass extending through the foramen ovale intracranially and into the cavernous sinus with rapid development of cavernous sinus syndrome. Cavernous sinus exenteration and radical neck dissection were performed for dedifferentiated adenoid cystic carcinoma with neuroendocrine features. Although we achieved an image-complete resection, her tumor ultimately recurred but responded well to chemoradiation, showing the importance of multidisciplinary approaches in complex skullbase malignancies Publication History Article published online: 27 February 2026 © 2026. Thieme. All rights reserved. Georg Thieme Verlag KG Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
Fields of Study & Subjects
Head and Neck Surgical Oncology
Salivary Gland Tumors Diagnosis and Treatment
Pituitary Gland Disorders and Treatments
Publication details
- Journal / source
- Journal of Neurological Surgery Part B Skull Base
- Volume
- 87
- Issue
- S 01
- Pages
- S1–S548
- Publication date
- 27 February 2026
- Language
- EN