Papillary Craniopharyngioma: Redefining the Role of Surgical Intervention
Abstract
A 75-year-old woman with bitemporal vision loss and normal pituitary function was found to have a solid-cystic suprasellar mass, suspicious for papillary craniopharyngioma given lack of calcifications on imaging. She underwent an endoscopic endonasal biopsy and decompression via a transsellar transtubercular approach. Pathology confirmed the diagnosis, so surgery was stopped. Postoperatively, her pituitary function remained intact. Given the tumor’s BRAF mutation sensitivity, targeted BRAF/MEK inhibitor therapy is reserved for recurrence, avoiding the need for radiation. Publication History Article published online: 27 February 2026 © 2026. Thieme. All rights reserved. Georg Thieme Verlag KG Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
Fields of Study & Subjects
Pituitary Gland Disorders and Treatments
Head and Neck Surgical Oncology
Neuroendocrine Tumor Research Advances
Publication details
- Journal / source
- Journal of Neurological Surgery Part B Skull Base
- Volume
- 87
- Issue
- S 01
- Pages
- S1–S548
- Publication date
- 27 February 2026
- Language
- EN