Cavernous Sinus Disconnection and Orbital Exenteration for Resection of a Breast Metastasis with Perineural Invasion
Abstract
Anterior skull base diseases involving the orbital region and perineural invasion into the cavernous region are rare, necessitating multidisciplinary management. A surgical case of a 71-year-old patient with recurrence of breast lobular carcinoma involving the left orbital, with preseptal, conal/extraconal extension, and perineural invasion of the cavernous sinus, requiring cavernous sinus disconnection and orbital exenteration via a crani-orbitozygomatic craniotomy and anterior clinoidectomy, is presented. Anatomical landmarks, surgical approach selection, and critical steps are discussed. Publication History Article published online: 27 February 2026 © 2026. Thieme. All rights reserved. Georg Thieme Verlag KG Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
Fields of Study & Subjects
Head and Neck Surgical Oncology
Ocular Oncology and Treatments
Pituitary Gland Disorders and Treatments
Publication details
- Journal / source
- Journal of Neurological Surgery Part B Skull Base
- Volume
- 87
- Issue
- S 01
- Pages
- S1–S548
- Publication date
- 27 February 2026
- Language
- EN