Nuances of the Endoscopic Endonasal Transcavernous Resection of A Recurrent and Refractory KNOSP 4 Macroprolactinoma
Abstract
Step-by-step nuances of the endoscopic endonasal medial transcavernous approach for a 23 y/o male who presented with a recurrent medically refractory Knosp 4 prolactinoma with right cavernous sinus invasion resistant to medication are discussed. Complete resection of the medial, posterior, and superior compartments, along with a significant decrease in prolactin level, was achieved postoperatively. There was a small residual tumor in the lateral compartment which could benefit from adjuvant radiotherapy. Publication History Article published online: 27 February 2026 © 2026. Thieme. All rights reserved. Georg Thieme Verlag KG Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
Fields of Study & Subjects
Pituitary Gland Disorders and Treatments
Head and Neck Surgical Oncology
Meningioma and schwannoma management
Publication details
- Journal / source
- Journal of Neurological Surgery Part B Skull Base
- Volume
- 87
- Issue
- S 01
- Pages
- S1–S548
- Publication date
- 27 February 2026
- Language
- EN