Mechanisms of early-onset prediabetes in women after pregnancy

Diabetologie und Stoffwechsel 2026 Open access

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Authors: Julia Sbierski‐Kind, Marlene Ganslmeier, Yanelys Kober, Yurong Cheng, Dorina Löffler, Hannah Ploppa, Corinna Dannecker, Andreas Vosseler, Lorenzo Semeia, Stephanie Kullmann, Kristina Bettecken, Sara Yvonne Brucker
+12 more Michael Roden, Stefan Richard Bornstein, Matthias Blüher, Jürgen Machann, Fritz Schick, Matthias Bernd Schulze, Norbert Stefan, Reiner Jumpertz von Schwartzenberg, Andreas Fritsche, Christoph Trautwein, Hubert T. Preissl, Andreas L. Birkenfeld
DOI: 10.1055/s-0046-1819947
Cited by: 0

Abstract

Background: Gestational diabetes mellitus (GDM) increases the risk of early-onset prediabetes. We hypothesized that the biological pathways mediating the transition from pregnancy to early-onset prediabetes one year postpartum differ between women with prior GDM and those with normoglyemic (NG) pregnancies using stratified longitudinal analyses with deep metabolic phenotyping.

Fields of Study & Subjects

Gestational Diabetes Research and Management Birth Development and Health Pregnancy and preeclampsia studies

Publication details

Journal / source
Diabetologie und Stoffwechsel
Volume
21
Publication date
1 May 2026