The Landscape of Genetically Driven Immune Disorders

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Authors: Xiao P. Peng, Jo L. Wilson, Dusan Bogunovic
Cited by: 1
References: 68

Abstract

AbstractThe increasingly widespread use of genetic diagnostic testing has shed light on genetic architectures, landscapes, and paradigms corresponding to the clinical and immune features of genetically driven immune disorders, but this wealth of information has also contributed additional layers of complexity for patient diagnosis and care. This review discusses concepts related to genetically driven immune disorders as they apply to current diagnostic and management strategies to help clinicians navigate these complexities.

Fields of Study & Subjects

Immunodeficiency and Autoimmune Disorders Diabetes and associated disorders Genomics and Rare Diseases

Publication details

Journal / source
NEJM Evidence
Publisher
Massachusetts Medical Society
Volume
5
Issue
6
Pages
EVIDra2400377–EVIDra2400377
Publication date
26 May 2026
Language
EN