Exertional Heat Illness in Active Populations

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Authors: Caroline Murphy, David W. DeGroot, Francis G. O’Connor
Cited by: 5
References: 68

Abstract

AbstractExertional heat illness (EHI) is a leading yet preventable cause of morbidity and mortality in active populations. EHI develops when the body's integrated thermoregulatory responses, including cardiovascular adjustments and evaporative cooling, are unable to dissipate the combined burden of metabolic heat production, environmental heat stress, clothing or protective equipment, and other contributing factors. This review examines the physiological mechanisms that underlie EHI and the effects of heat stress on the exercising heart. We also summarize best practices for the prevention, recognition, and management of exertional heat illness.

Fields of Study & Subjects

Thermoregulation and physiological responses Exercise and Physiological Responses Climate Change and Health Impacts

Publication details

Journal / source
NEJM Evidence
Publisher
Massachusetts Medical Society
Volume
5
Issue
5
Pages
EVIDra2500270–EVIDra2500270
Publication date
28 April 2026
Language
EN