Digital Twin–Guided Ablation for Ventricular Tachycardia

New England Journal of Medicine 2026 Open access

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Authors: Jonathan Chrispin, Adityo Prakosa, Eugene Kholmovski, Aravindan Kolandaivelu, Amanda Barcelon, Konstantinos N. Aronis, Ronald D. Berger, Hugh Calkins, Natalia Trayanova
DOI: 10.1056/nejmc2517822
Cited by: 11
References: 5

Abstract

In a 10-patient feasibility study, heart digital twins were used to guide VT ablation. Afterward, VT was noninducible in all patients; at a mean follow-up of 13 months, 8 patients were free of recurrence, without drug therapy.

Fields of Study & Subjects

Cardiac Arrhythmias and Treatments Cardiac pacing and defibrillation studies Cardiac tumors and thrombi

Publication details

Journal / source
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Volume
394
Issue
13
Pages
1345–1347
Publication date
1 April 2026
Language
EN