Reduction of Antihypertensive Treatment in Nursing Home Residents
Abstract
To the Editor: The results of the RETREAT-FRAIL trial reported by Benetos et al. (Nov. 20 issue) 1 regarding progressive discontinuation of antihypertensive medications in nursing home residents with a mean age of 90 years are highly relevant for this vulnerable patient group whose care is often complicated by polypharmacy. However, it is important to recognize that this group of the oldest adults is very heterogeneous, and decision making for drug therapy needs to be individualized. Among all the trial participants, reducing the number of antihypertensive medications (step-down strategy) did not affect the incidence of death from any cause. However, Figure . . .
Fields of Study & Subjects
Pharmaceutical Practices and Patient Outcomes
Geriatric Care and Nursing Homes
Blood Pressure and Hypertension Studies
Publication details
- Journal / source
- New England Journal of Medicine
- Volume
- 394
- Issue
- 9
- Pages
- 930–933
- Publication date
- 25 February 2026
- Language
- EN