Restoring Function to a Variant of p53 in Solid Tumors
Abstract
The author describes the scientific foundations of a study of rezatapopt, which targets a variant form of p53, to treat patients with solid tumors.
Fields of Study & Subjects
Cancer-related Molecular Pathways
Chromatin Remodeling and Cancer
PI3K/AKT/mTOR signaling in cancer
Publication details
- Journal / source
- New England Journal of Medicine
- Volume
- 394
- Issue
- 9
- Pages
- 922–925
- Publication date
- 25 February 2026
- Language
- EN